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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNA3
All Species:
0.3
Human Site:
S497
Identified Species:
0.67
UniProt:
P22001
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22001
NP_002223.3
575
63842
S497
E
T
E
G
E
E
Q
S
Q
Y
M
H
V
G
S
Chimpanzee
Pan troglodytes
XP_524797
575
63732
A497
E
T
E
G
E
E
Q
A
Q
Y
M
H
V
G
S
Rhesus Macaque
Macaca mulatta
XP_001101652
575
63544
A497
E
T
E
G
E
E
Q
A
Q
Y
M
H
V
G
S
Dog
Lupus familis
XP_547231
467
51847
Q390
T
E
G
E
E
Q
A
Q
Y
M
H
V
G
S
C
Cat
Felis silvestris
Mouse
Mus musculus
P16390
528
58545
A450
E
T
E
G
E
E
Q
A
Q
Y
M
H
V
G
S
Rat
Rattus norvegicus
P15384
525
58406
A447
E
T
E
G
E
E
Q
A
Q
Y
M
H
V
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508752
534
58831
I457
D
E
G
V
E
Q
A
I
T
G
K
E
V
P
T
Chicken
Gallus gallus
Q7T199
516
58965
G439
M
C
P
T
T
L
G
G
K
I
V
G
T
L
C
Frog
Xenopus laevis
P22739
499
56683
E422
Y
F
Y
H
R
E
T
E
G
E
E
Q
A
Q
Y
Zebra Danio
Brachydanio rerio
XP_002666485
515
58425
Y438
V
I
V
S
N
F
N
Y
F
Y
H
R
E
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08510
655
74175
Q495
E
T
D
Q
E
E
M
Q
S
Q
N
F
N
H
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.4
74.4
N.A.
87.4
87.6
N.A.
68.6
56.8
67.1
76
N.A.
53.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
76.6
N.A.
89.5
89.3
N.A.
74.4
68.1
74.9
81.5
N.A.
62.7
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
6.6
N.A.
93.3
93.3
N.A.
13.3
0
6.6
6.6
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
33.3
13.3
6.6
6.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
37
0
0
0
0
10
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
19
% C
% Asp:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
55
19
46
10
73
64
0
10
0
10
10
10
10
0
10
% E
% Phe:
0
10
0
0
0
10
0
0
10
0
0
10
0
0
0
% F
% Gly:
0
0
19
46
0
0
10
10
10
10
0
10
10
46
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
19
46
0
10
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% L
% Met:
10
0
0
0
0
0
10
0
0
10
46
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
10
0
19
46
19
46
10
0
10
0
10
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
10
10
0
0
0
0
10
46
% S
% Thr:
10
55
0
10
10
0
10
0
10
0
0
0
10
10
10
% T
% Val:
10
0
10
10
0
0
0
0
0
0
10
10
55
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
10
10
55
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _